Anesthetics and hyperpolarization...?!
Question: Anesthetics and hyperpolarization!.!.!.!?
I read that an anesthetic molecule attaches to a receptor protein and causes hyperpolarization!.!. as it prolongs the opening of the channel!.!.
So, i was wondering what does hyperpolarization actually do to the body!? As in what difference does it make!?Www@Answer-Health@Com
So, i was wondering what does hyperpolarization actually do to the body!? As in what difference does it make!?Www@Answer-Health@Com
Answers:
This is a big question in research on anesthetic mechanisms!.
Individual neurons in the brain receive both excitatory (depolarizing) and inhibitory (hyperpolarizing) signals from other neurons!. If there is considerably more excitation than inhibition, then that neuronal will fire an action potential and spread a signal to other neurons!. The working hypothesis is that anesthetics tilt the balance of signals reaching a neuron towards more inhibition!. That means fewer neurons will fire action potentials and there will be less signaling between neurons!. Presumably, this would temporarily turn off some processes, like awareness and pain reception!. And those are some of the signs of being anesthetized!.Www@Answer-Health@Com
Individual neurons in the brain receive both excitatory (depolarizing) and inhibitory (hyperpolarizing) signals from other neurons!. If there is considerably more excitation than inhibition, then that neuronal will fire an action potential and spread a signal to other neurons!. The working hypothesis is that anesthetics tilt the balance of signals reaching a neuron towards more inhibition!. That means fewer neurons will fire action potentials and there will be less signaling between neurons!. Presumably, this would temporarily turn off some processes, like awareness and pain reception!. And those are some of the signs of being anesthetized!.Www@Answer-Health@Com