Carbamazepine?!
Question: Carbamazepine!?
My dr gave me 3 scripts one being carbamazepine but i red that you could get SJS and TEN from it how likely is this!? I have never had a liver probelm but i am over weight due to depression ( I eat because of it but i am dieting) Also they gaveme a script and i got the meds and it said dont take if you are taking tramadol and i take Tramadol for TMJ (a jaw problem) but i havent had an ain butt recently the only way ican sleep is taking 100mg tramadol 50mg benadryl and 1000 mg tylonal PM I dold my dr this and she didnt say anything about it im wondering if they say on the bottle dont take with tramadol perioud or how long you should not take tramadol ect!. Also I would like to know how you feel on the carbamazepine does it help with the mood swings!. Or does it just make you to tired to care!.Www@Answer-Health@Com
Answers:
1) Dermatological effects of carbamazepine that are more common include photosensitivity, alopecia, urticaria, and alterations in skin pigmentation, exfoliative dermatitis, erythema multiforme and erythema nodosum, purpura, aggravation of disseminated lupus erythematosus, and diaphoresis!. In certain cases, discontinuation of therapy may be necessary!. Serious but rare adverse reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis (TEN) may occur and require immediate drug discontinuation and appropriate medical attention; in rare cases, fatalities have occurred!. It is recommended that Asian patients undergo a genetic blood test prior to initiation of carbamazepine treatment, since an inherited variant of an immune system gene (HLA-B 1502) found primarily in Asians is associated with the development of these skin reactions!. [1]
2) Carbamazepine induces cytochrome P450 isoenzyme 2D6, which induces the metabolism of tramadol!. So taking your regular dose of 100mg per day may not have the same pain alleviating effects as when you weren
2) Carbamazepine induces cytochrome P450 isoenzyme 2D6, which induces the metabolism of tramadol!. So taking your regular dose of 100mg per day may not have the same pain alleviating effects as when you weren
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