Janumet? I started taking it today.......?!


Question: 50/500 mg twice a day. I couldn't tolerate the Metformin alone and was only on the Januvia and Byetta. I am not diabetic. I have insulin resistance due to having polycystic ovarian syndrome and no matter what I do I can't lose weight.

I am asking for your feedback on Janumet. Does it work? What are the side effects you experienced?


Answers: 50/500 mg twice a day. I couldn't tolerate the Metformin alone and was only on the Januvia and Byetta. I am not diabetic. I have insulin resistance due to having polycystic ovarian syndrome and no matter what I do I can't lose weight.

I am asking for your feedback on Janumet. Does it work? What are the side effects you experienced?

What is the most important information I should know about JANUMET?

Metformin hydrochloride, one of the ingredients in JANUMET, can cause a rare but serious side effect called lactic acidosis (a build-up of lactic acid in the blood) that can cause death. Lactic acidosis is a medical emergency and must be treated in a hospital.

Stop taking JANUMET and call your doctor right away if you get any of the following symptoms of lactic acidosis:
You feel very weak and tired.
You have unusual (not normal) muscle pain.
You have trouble breathing.
You have unexplained stomach or intestinal problems with nausea and vomiting, or diarrhea.
You feel cold, especially in your arms and legs.
You feel dizzy or lightheaded.
You have a slow or irregular heart beat.
You have a higher chance of getting lactic acidosis if you:
have kidney problems.
have liver problems.
have congestive heart failure that requires treatment with medicines.
drink a lot of alcohol (very often or short-term "binge" drinking).
get dehydrated (lose a large amount of body fluids). This can happen if you are sick with a fever, vomiting, or diarrhea. Dehydration can also happen when you sweat a lot with activity or exercise and don't drink enough fluids.
have certain x-ray tests with injectable dyes or contrast agents.
have surgery.
have a heart attack, severe infection, or stroke.
are 80 years of age or older and have not had your kidney function tested.
What is JANUMET?

JANUMET tablets contain two prescription medicines, sitagliptin (JANUVIA?2) and metformin. JANUMET is used along with diet and exercise to lower blood sugar in patients with type 2 diabetes who have already been treated with either JANUVIA or metformin and their blood sugar is not controlled well enough, or patients who are currently taking both JANUVIA and metformin as separate medicines.

General information about the use of JANUMET:
helps to improve the levels of insulin after a meal.
helps the body respond better to the insulin it makes naturally.
decreases the amount of sugar made by the body.
is unlikely to cause low blood sugar (hypoglycemia).
JANUMET has not been studied in children under 18 years of age.

Who should not take JANUMET?

Do not take JANUMET if you:
have type 1 diabetes.
have certain kidney problems.
have conditions called metabolic acidosis or diabetic ketoacidosis (increased ketones in the blood or urine).
are going to receive an injection of dye or contrast agents for an x-ray procedure, JANUMET will need to be stopped for a short time. Talk to your doctor about when to stop JANUMET and when to start again. See



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